If you’re someone who routinely gets nervous and stressed

However, the ability of 11 to regulate GC target genes in human skin has not been investigated.You will treat human skin samples with vehicle, cortisone (11 substrate), cortisol (11 product) or cortisone and an 11 inhibitor. GC target gene expression will be measured by quantitative PCR following mRNA extraction and cDNA synthesis. Corresponding changes in protein expression will be confirmed by immunohistochemistry.

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